The Science

Longevity Isn't Magic.
It's Biology.

Every VEYA formula is built on peer-reviewed research. Here's the science behind what we make, why the doses are what they are, and why NAD+ and NMN are at the center of modern longevity research.

60+
Peer-reviewed studies
90%
NAD+ increase at 500mg
50%
NAD+ drop by age 50
2wks
To measurable NAD+ rise
Why NAD+ Matters

Your Cells Run on
NAD+. And It Declines.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell. It's essential for ATP production, DNA repair, sirtuin activation, and cellular signaling.

The problem: NAD+ levels drop approximately 50% between your 20s and your 50s. This decline is strongly linked in the research to reduced energy, slower cognitive function, longer recovery times, and accelerated biological aging.

No diet meaningfully reverses this decline. Supplementation at a therapeutic dose does — and the research is unambiguous about what that dose is.

Relative NAD+ Level by Age Decade
100%
Age 20
82%
Age 30
65%
Age 40
50%
Age 50
37%
Age 60
27%
Age 70
Based on Zhu et al., 2015 and supporting literature
Research Foundation

The Papers That
Built Our Formulas.

These are the specific studies that determined our ingredient choices and dose thresholds.

Nutrients · 2017

Oral NAD+ raises whole-blood levels by up to 90% in 60 days

Human clinical trial: 500mg daily raised whole-blood NAD+ by 90% within 60 days — establishing the therapeutic threshold used in our formula.

500mg = clinical threshold
Cell Metabolism · 2013

NAD+ repletion reverses age-related muscle deterioration

Harvard landmark study: elevating NAD+ restored muscle function, endurance, and mitochondrial health in aging subjects. First major causal evidence linking NAD+ decline to physical aging.

Decline is causal, not correlation
Nature Metabolism · 2020

NAD+ improves metabolic and cardiovascular health in humans

Double-blind human trial: oral NAD+ measurably raised blood NAD+ within 2 weeks and improved metabolic markers and vascular function in healthy middle-aged adults.

2-week measurable effect in humans
Science · 2003 · Cell · 2013

Resveratrol directly activates SIRT1 and SIRT3 longevity proteins

Sinclair's Harvard research established that Resveratrol activates sirtuins — the cellular proteins that regulate DNA repair, inflammation, and metabolic efficiency. Sirtuins are powered by NAD+.

Sirtuin activation amplifies NAD+ effect
npj Aging · 2021

NAD+ decline is a primary driver of multiple age-related diseases

Comprehensive review linking NAD+ decline to neurodegeneration, cardiovascular disease, and metabolic dysfunction — establishing NAD+ restoration as one of the most evidence-supported longevity interventions available.

Systemic relevance, not single-system
J. Nutritional Biochemistry · 2016

Quercetin significantly reduces oxidative stress and inflammation

Controlled clinical trials confirm Quercetin at 250mg lowers inflammatory biomarkers and oxidative stress — creating the environment where NAD+ can drive cellular repair rather than fighting inflammation.

Synergistic environment for NAD+ activity
90%
Increase in cellular NAD+ at 500mg (Nutrients, 2017)
1.7×
Higher muscle NAD+ when NMN + Resveratrol are combined
2wks
Time to measurable blood NAD+ rise in human trials
60+
Peer-reviewed papers across VEYA formula ingredients
How It Works

Two Pathways.
One Outcome.

NAD+ and NMN raise cellular NAD+ through different routes — which is why stacking them is more effective than either alone.

Direct NAD+

VEYA NAD+ — Immediate

Takes the direct route. No conversion required. Enters the bloodstream as the active coenzyme and is taken up by cells directly — particularly reliable for adults 40+ whose enzymatic conversion capacity has declined.

You take 500mg NAD+
Absorbed directly into blood
Direct cellular uptake
Active NAD+ in cells ✓
NMN Precursor

VEYA NMN — Biosynthesis

Works through your body's natural NAD+ synthesis pathway — the same route your biology uses. Favoured by adults 30–45 and biohackers who prefer the precursor approach. Stacks powerfully with direct NAD+.

You take 500mg NMN
Absorbed via Slc12a8 transporters
NMNAT enzyme converts NMN → NAD+
NAD+ restored in cells ✓
What's In Each Formula
NAD+ / NMN
500mg — Primary Active

The core coenzyme or its most direct precursor — at the clinical dose the research actually uses. Not a token amount.

🍇
Trans-Resveratrol
100–150mg — SIRT Activator

Activates SIRT1 and SIRT3. NMN + Resveratrol raises NAD+ in key tissues by 1.6–1.7× versus either alone. At 98% purity.

🍎
Quercetin
250mg — Environment Optimizer

Reduces oxidative stress so NAD+ drives repair rather than managing inflammation. In our NAD+ formula. Sophora japonica source.

The Dose Principle

Why Dose Is
Everything. Literally.

The most common failure mode in supplements isn't fake ingredients — it's real ingredients at doses that don't work. A clinical study uses 500mg. The brand puts 50mg in the bottle. The customer sees the ingredient name and assumes it's the same thing.

It isn't. Sub-therapeutic doses produce sub-therapeutic results. The research on NAD+ is unambiguous: 500mg is the threshold at which meaningful, measurable increases in cellular NAD+ occur.

We built VEYA around one commitment: our doses match the clinical literature that earned them. Not the minimum that lets us put an ingredient on a label.

NAD+ Dose Comparison
VEYA
500mg
Industry avg.
~110mg
Most brands
50mg
VEYA meets the clinical threshold. Most brands don't come close.
Apply the Science

The Research Is Clear.
The Dose Is Right.

NAD+ at 500mg. NMN at 99%+ purity. Resveratrol at 98% trans-form. Backed by 60 days and our full guarantee. Ships across the US.